ointment base formulation

The different thickeners work in different ways. This is not an example of the work produced by our Essay Writing Service. For example, some topical steroids will be classified one or two strengths higher when moving from cream to ointment. Uniformity of Drug Content Predetermined amount of ointment formulation was tak-en from three different regions of an ointment jar and was dissolved in methanol. an ointment base is selected that will produce a product that may be readily applied to the required site. After preparing the ointment, one must select an ointment jar that will just hold all of the formulation. Some are stronger, others weaker. An ointment-like base comprises a blend of at least one topically acceptable alkyl ester of an aromatic carboxylic acid and at least one topically acceptable dialkyl ester of a hydroxyalkanedicarboxylic acid, the ratio of the two esters being from about 1:3 to 4:1. pH of these solutions was measured using the Mettler Toledo InLab®Micro pH probe (Electrolyte 3 mol/L KCl). 4708 words (19 pages) Essay. Formulation requirement: efficacy, safety, and quality. You can view samples of our professional work here. Convenient to take or administer . 1st Jan 1970 Education Reference this Disclaimer: This work has been submitted by a university student. As a rule of thumb, an ointment base is more occlusive and will drive the medication into the skin more rapidly than a solution or cream base. Retain quality throughout shelf life & usage period In light of the high drug content, this point is particularly important in the formulation of pastes. Begin by taking some ointment and fill the bottom of the ointment jar, and use the spatula to put some ointment into the crevices. You can mix several thickeners in … Thickeners are all substances that make a cream or ointment out of the liquid oil and water. Formulation of ointment and cream. The ointment base was prepared and formulation of ointment was done by incorporating the active ingredients in most effective ratio in the base by trituration. Provide drug in a form for absorption or other delivery to the target . to get final ointment concentrations of 1% w/v,5%w/v, and 10% w/v. Contain accurate dose . Continue adding ointment to the jar again using the spatula to put the ointment along the sides of the jar. And some are greasy, others give protection to the skin and others have their own healing qualitiy. A medication's potency often is changed with its base. PHM4153 Dosage Design 2 2011/12. Choice of base formulation.

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